Search on: SREBP PROTEINS 
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Descriptor English:   Sterol Regulatory Element Binding Proteins 
Descriptor Spanish:   Proteínas de Unión a los Elementos Reguladores de Esteroles 
Descriptor Portuguese:   Proteínas de Ligação a Elemento Regulador de Esterol 
Synonyms English:   SREBP Proteins  
Tree Number:   D12.776.260.103.500.750
D12.776.260.108.092.750
D12.776.930.125.500.750
D12.776.930.127.092.750
Definition English:   Sterol regulatory element binding proteins are basic helix-loop-helix leucine zipper transcription factors that bind the sterol regulatory element TCACNCCAC. They are synthesized as precursors that are threaded into the MEMBRANES of the ENDOPLASMIC RETICULUM. 
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50945 
Unique Identifier:   D051779 

Occurrence in VHL:
 

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